.Italian painter of the Umbrian school, who probably studied with Piero della Francesca. He worked in Cortona, where some of his paintings have remained. Subsequently he worked in the Cathedral of Perugia, in Volterra, and at Monte Oliveto before undertaking (1499) the decoration of the Cappella Nuova in the Orvieto Cathedral. There he represented the apocalyptic series of the Story of the Anti-Christ, the End of the World, the Resurrection of the Bodies, Paradise, and the Inferno, as well as figurations from antique poems and the Divine Comedy. The infernal scenes are remarkable for their imaginative evocation of fiends and tortures of Hell. Michelangelo was influenced by his powerful treatment of anatomy and the vivid realism he used for dramatic ends. Signorelli's paintings in the Vatican, where he went in 1508, were later sacrificed to make way for some of Raphael's work.